Wick H
Int Z Vitam Ernahrungsforsch Beih. 1979;18:33-44.
Complete AS mixtures which permit prolonged parenteral feeding are known. It is possible to achieve normal growth even in nursing infants with such solutions (reference should be made to the contributions of Professor Riccour and Professor Schärli). On the other hand the composition of an AS solution of maximum biological value, e.g. for the growing body, is not yet known. Improvements in this respect can be envisaged although they are relevant only to certain patients. Changes in the method administration of AS may affect the biological value. Continuous administration throughout the 24 hours by-passing the portal vein, as is usual today, must considerably impair the capacity of the liver to regulate the pattern of plasma amino acids. Possibly, an approximation to physiological proportions is possible and useful through intermittent administration. Further progress in this aspect of parenteral feeding can undoubtedly be expected.