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一名多发性骨髓瘤患者发生海藻希瓦氏菌菌血症及相关蜂窝织炎。

Shewanella alga bacteremia and associated cellulitis in a patient with multiple myeloma.

作者信息

Krsnik Isabel, Arribalzaga Karmele, Romanyk Juan

机构信息

Servicio de Hematología, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain.

出版信息

Haematologia (Budap). 2002;32(1):79-80. doi: 10.1163/156855902760262808.

Abstract

Shewanella alga is a gram-negative bacillus found in all types of water as well as in a variety of tainted food. It has rarely been associated with human disease, either in healthy or in immunocompromised patients. We report a 66-year-old man with a multiple myeloma who developed a cellulitis in both forearms in the course of a Shewanella bacteremia. He had a renal insufficiency and was moderately neutropenic after chemotherapy (vincristine, adriamycin, dexamethasone). Outcome was good after treatment with ceftazidime-amikacin despite all the risk factors. Shewanella isolation may be clinically significant. Haematological patients constitute a group of risk as increasingly aggressive chemotherapy regimens are used. Clinical outcome is not necessarily bad.

摘要

海藻希瓦氏菌是一种革兰氏阴性杆菌,存在于各种类型的水中以及多种受污染的食物中。它很少与人类疾病相关,无论是在健康患者还是免疫功能低下的患者中。我们报告了一名66岁的多发性骨髓瘤患者,在海藻希瓦氏菌败血症过程中双侧前臂发生蜂窝织炎。他有肾功能不全,化疗(长春新碱、阿霉素、地塞米松)后出现中度中性粒细胞减少。尽管存在所有风险因素,但使用头孢他啶-阿米卡星治疗后结果良好。分离出海藻希瓦氏菌可能具有临床意义。随着越来越积极的化疗方案的使用,血液学患者构成了一组风险人群。临床结果不一定很差。

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