Henrick Clive A, Ko Jinren, Nguyen Jack, Burleson Jim, Lindahl George, Van Gundy Douglas, Edge Julie M
Zoecon Research and Development, Palo Alto, CA 94303, USA.
J Am Mosq Control Assoc. 2002 Sep;18(3):214-21.
Evidence that amphibian deformities are on the rise has prompted a number of researchers to question a variety of natural and man-made substances, including chemicals such as s-methoprene (trademark Altosid), an insect growth regulator applied to water bodies for mosquito control. Despite conclusions reached by the U.S. Environmental Protection Agency and a considerable body of scientific evidence demonstrating that it is unlikely that s-methoprene or any of its degradation products are causing the high rates of deformities found in Minnesota and other states, concerns persist about potential negative impacts of s-methoprene on nontarget species, specifically anurans. Water analyses in field and laboratory conditions and a comparison of reported Altosid use with reported frog deformities in Minnesota demonstrate that a connection between frog deformities and Altosid use is unlikely. These results indicate that factors other than s-methoprene and its degradation products are contributing to the recent outbreak of frog deformities.
有证据表明两栖动物畸形现象正在增加，这促使许多研究人员对多种天然和人造物质提出质疑，其中包括诸如烯虫酯（商标名：Altosid）之类的化学物质，烯虫酯是一种用于水体以控制蚊子的昆虫生长调节剂。尽管美国环境保护局已得出结论，且有大量科学证据表明烯虫酯或其任何降解产物不太可能导致在明尼苏达州和其他州发现的高畸形率，但人们仍对烯虫酯对非目标物种（特别是无尾目动物）的潜在负面影响感到担忧。在野外和实验室条件下进行的水质分析，以及将明尼苏达州报告的Altosid使用情况与报告的青蛙畸形情况进行比较，结果表明青蛙畸形与Altosid的使用之间不太可能存在关联。这些结果表明，除烯虫酯及其降解产物之外的其他因素导致了近期青蛙畸形现象的爆发。
