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氧化氘稀释法测量新加坡人身体脂肪的有效性。

Validity of deuterium oxide dilution for the measurement of body fat among Singaporeans.

作者信息

Deurenberg-Yap Mabel, Deurenberg Paul

机构信息

National University of Singapore.

出版信息

Food Nutr Bull. 2002 Sep;23(3 Suppl):34-7.

PMID:12362808
Abstract

Body fat percent (BF%) was measured in 108 adult Chinese, 76 Malays, and 107 Indians in Singapore by densitometry, deuterium oxide dilution (hydrometry), dual energy x-ray absorptiometry (DXA) and a chemical four-compartment model (BF%4c). The hydration of the fat-free mass (FFM) was calculated. Subjects ranged in age from 18 to 69 years and their body mass index ranged from 16 to 40 kg/m2. BF%4c for the various subgroups were: Chinese females (33.5 +/- 7.5%), Chinese males (24.4 +/- 6.1%), Malay females (37.8 +/- 6.3%), Malay males (26.0 +/- 7.6%), Indian females (38.2 +/- 7.0%) and Indian males (28.1 +/- 5.5%). Biases were found between BF%4c and BF% measured by 2-compartment models (hydrometry, densitometry, DXA), with systematic underestimation by DXA and densitometry. On a group level hydrometry had the lowest bias while DXA gave the highest bias. When validated against BF%4c, 2-compartment models were found to be unsuitable for accurate measures of body fat due to high biases at the individual level and the violation of assumptions of constant hydration of FFM and density FFM among the ethnic groups. On a group level the best 2-compartment model for measuring body fat was found to be hydrometry.

摘要

采用密度测定法、氧化氘稀释法(水比重测定法)、双能X线吸收法(DXA)和化学四室模型(BF%4c),对新加坡108名成年中国人、76名马来人和107名印度人的体脂百分比(BF%)进行了测量。计算了去脂体重(FFM)的水合作用。受试者年龄在18至69岁之间,体重指数在16至40kg/m²之间。各亚组的BF%4c分别为:中国女性(33.5±7.5%)、中国男性(24.4±6.1%)、马来女性(37.8±6.3%)、马来男性(26.0±7.6%)、印度女性(38.2±7.0%)和印度男性(28.1±5.5%)。发现BF%4c与两室模型(水比重测定法、密度测定法、DXA)测量的BF%之间存在偏差,DXA和密度测定法存在系统性低估。在组水平上,水比重测定法的偏差最低,而DXA的偏差最高。当与BF%4c进行验证时,发现两室模型由于在个体水平上偏差较大以及违反了各民族FFM水合作用恒定和FFM密度恒定的假设,不适用于准确测量体脂。在组水平上,测量体脂的最佳两室模型是水比重测定法。

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