[头颈部癌的前哨淋巴结活检。在头颈部癌的治疗中使用这种新手术技术有指征吗?]

[Sentinel node biopsy in head and neck cancer. Is there an indication for use of this new surgical technique in the treatment of head and neck cancer?].

作者信息

Bilde Anders, von Buchwald Christian, Dreyer Marianne, Eigtved Annika I

机构信息

H:S Rigshospitalet, HovedOrtoCenteret, øre-naese-halskirurgisk klinik, Diagnostisk Center, klinik for klinisk fysiologi og nuklearmedicin.

出版信息

Ugeskr Laeger. 2002 Sep 9;164(37):4276-80.

DOI:
Abstract

Management of the clinically N0 neck in head and neck squamous cell carcinoma remains controversial. Since lymph node metastasis reduces the five-year survival by up till 50%, the need for an accurate diagnostic procedure is necessary. The sentinel node, being the initial lymph node to which the primary tumour drains, is believed to be invaded by early metastasis. Identification of the sentinel node by means of a dye or isotope or a combination, and surgical removal followed by histological examination verifies the involvement of the regional glands. At present few and limited materials on head and neck cancers exist, primarily on oral and oropharyngeal cancers. The techniques used are various and not without difficulties. To evaluate the feasibility of the sentinel node biopsy in head and neck cancer, it is proposed to perform a nationwide cohort study that comprises all minor oral and oropharyngeal cancers (T1, T2, N0).

摘要

头颈部鳞状细胞癌临床N0颈部的处理仍存在争议。由于淋巴结转移会使五年生存率降低多达50%,因此需要一种准确的诊断程序。前哨淋巴结作为原发肿瘤引流的首个淋巴结,被认为会被早期转移侵犯。通过染料或同位素或两者结合来识别前哨淋巴结,并进行手术切除,随后进行组织学检查,可证实区域淋巴结是否受累。目前关于头颈部癌症的资料很少且有限,主要是关于口腔和口咽癌的。所使用的技术多种多样且并非没有困难。为评估前哨淋巴结活检在头颈部癌中的可行性,建议开展一项全国性队列研究,纳入所有小型口腔和口咽癌(T1、T2、N0)。

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