苍白球切开术的微电极记录：是必需的、有益的还是危险的？

Microelectrode recording for pallidotomy: mandatory, beneficial or dangerous?

作者信息

Honey C R, Berk C, Palur R S, Schulzer M

机构信息

Surgical Centre for Movement Disorders, University of British Columbia, Vancouver, Canada.

出版信息

Stereotact Funct Neurosurg. 2001;77(1-4):98-100. doi: 10.1159/000064606.

DOI:10.1159/000064606

PMID:12378064

Abstract

There is an active debate regarding whether pallidotomy should be performed with microelectrode recording or macroelectrode stimulation. A meta-analysis was performed on the published reports (1992-2000) of unilateral pallidotomy for Parkinson's disease to determine if the outcome or complications of this procedure significantly differed between these two techniques. Papers were excluded if they followed a cohort of less than ten patients, had follow-up less than three months, or included previously reported patients. There were no significant differences between the two techniques in improvement of dyskinesia (p = 0.66) or UPDRS motor score (p = 0.62). Microelectrode recording had a significantly higher (p = 0.012) intracerebral hemorrhage rate (1.3 +/- 0.4%) compared to macroelectrode stimulation (0.2 +/- 0.2%).

摘要

关于苍白球切开术是应采用微电极记录还是宏观电极刺激进行，目前存在着激烈的争论。对已发表的（1992 - 2000年）关于帕金森病单侧苍白球切开术的报告进行了荟萃分析，以确定这两种技术在此手术的结果或并发症方面是否存在显著差异。如果论文所追踪的患者少于10例、随访时间少于3个月或纳入了先前已报告的患者，则将其排除。在运动障碍改善方面（p = 0.66）或统一帕金森病评定量表（UPDRS）运动评分方面（p = 0.62），这两种技术之间没有显著差异。与宏观电极刺激（0.2 +/- 0.2%）相比，微电极记录的脑出血发生率显著更高（p = 0.012），为（1.3 +/- 0.4%）。