Ben-Aroya Zahi, Benharroch Daniel, Hallak Mordechai, Kachko Leonid, Katz Miriam
Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, P.O. Box 5, Holon 58100, Israel.
J Reprod Med. 2002 Sep;47(9):767-9.
Inflammatory pseudotumor (IPT), also called plasma cell granuloma, is a rare, benign, tumorlike lesion composed of proliferating spindle cells admixed with an inflammatory infiltrate and usually affecting the lungs. Other locations can also be affected.
An 18-year-old woman complained of abdominal pain and discomfort. Sonographic evaluation revealed a hyperechogenic mass measuring 32 x 36 mm and located between the right ovary and uterus. CBC showed mild leukocytosis. Laparoscopic resection of the mass revealed histologically an inflammatory pseudotumor.
IPT may occur at any age and affects both sexes equally. The clinical presentation usually includes fever, leukocytosis and weight loss, although many cases are asymptomatic, especially in the pelvis. The lesion usually presents with distinct borders and a firm consistency and is tan to white. The course of IPT is usually benign and self-limited. Surgical resection is the most common therapy, whereas corticosteroids and, in rare cases, chemotherapy are used. Recurrences have been described. Because of the rarity of this condition, it is unusual for the diagnosis to be made preoperatively.
炎性假瘤(IPT),也称为浆细胞性肉芽肿,是一种罕见的良性肿瘤样病变,由增生的梭形细胞与炎性浸润混合组成,通常累及肺部。其他部位也可受累。
一名18岁女性主诉腹痛和不适。超声检查发现一个大小为32×36mm的高回声肿块,位于右卵巢和子宫之间。血常规显示轻度白细胞增多。腹腔镜切除肿块的组织学检查显示为炎性假瘤。
IPT可发生于任何年龄,男女均可受累。临床表现通常包括发热、白细胞增多和体重减轻,尽管许多病例无症状,尤其是在盆腔。病变通常边界清晰,质地硬,呈棕褐色至白色。IPT的病程通常是良性的且自限性。手术切除是最常见的治疗方法,而皮质类固醇以及在罕见情况下使用化疗。已有复发的报道。由于这种疾病罕见,术前诊断并不常见。