Magyar M Tünde, Nam Eun-Mi, Csiba László, Ritter Martin A, Ringelstein E Bernd, Droste Dirk W
Department of Neurology, University of Debrecen, Hungary.
Neurol Res. 2002 Oct;24(7):705-8. doi: 10.1179/016164102101200618.
Carotid bruits are supposed to indicate the presence of high-grade common carotid or extracranial internal carotid artery stenosis in a large proportion of patients. Using a stethoscope, we prospectively auscultated 273 carotid arteries of 145 patients blinded to the results of a complete extracranial and intracranial Doppler investigation including extracranial color-coded duplex ultrasound. Fifty-four arteries showed stenosis of > or = 50%-99%, or occlusion of the extracranial internal or the common carotid artery. In 25 of these arteries, a bruit was present. In 9 out of 16 patients with extracranial stenosis from 70%-99%, a bruit was detected. In one additional patient with a middle-grade external carotid artery stenosis, a bruit was also present. In seven additional patients, a bruit was present in the absence of any carotid artery stenosis, cardiac vitium or goiter. The sensitivity of carotid auscultation for the detection of a 70%-99% stenosis of the common or extracranial internal carotid artery was 56% and specificity was 91%. The positive predictive value of a bruit found during carotid auscultation was 27%, and the negative predictive value of a normal auscultation was 97%. Carotid auscultation is a useful screening procedure in the detection of carotid stenosis or occlusion, but requires confirmation by carotid ultrasound.
在大部分患者中,颈动脉杂音被认为提示存在重度颈总动脉或颅外段颈内动脉狭窄。我们使用听诊器,对145例患者的273条颈动脉进行了前瞻性听诊,这些患者对包括颅外彩色编码双功超声在内的完整颅外和颅内多普勒检查结果不知情。54条动脉显示狭窄程度≥50% - 99%,或颅外段颈内动脉或颈总动脉闭塞。其中25条动脉有杂音。在16例颅外段狭窄程度为70% - 99%的患者中,有9例检测到杂音。另外,在1例中度颈外动脉狭窄患者中也发现有杂音。还有7例患者,在没有任何颈动脉狭窄、心脏瓣膜病或甲状腺肿的情况下出现了杂音。颈动脉听诊检测颈总动脉或颅外段颈内动脉70% - 99%狭窄的敏感性为56%,特异性为91%。颈动脉听诊发现杂音的阳性预测值为27%,听诊正常的阴性预测值为97%。颈动脉听诊是检测颈动脉狭窄或闭塞的一种有用的筛查方法,但需要通过颈动脉超声进行确认。