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经主动脉窦行左心室流出道心动过速的冷盐水灌注导管消融术

[Cooled tip ablation of left ventricular outflow tract tachycardia through the aortic sinus of valsalva].

作者信息

Kurzidim K, Neumann T, Vukajlovic D, Güttler N, Sperzel J, Bahavar H, Hamm C W, Pitschner H F

机构信息

Kerckhoff-Klinik, Kardiologie Benekestr. 2-8 61231 Bad Nauheim, Germany.

出版信息

Z Kardiol. 2002 Oct;91(10):796-805. doi: 10.1007/s00392-002-0839-6.

Abstract

BACKGROUND

Monomorphic tachycardia with an epicardial site of the arrhythmic focus in the left ventricular outflow tract (LVOT) usually cannot be ablated by an endocardial approach. We describe the use of cooled tip catheter ablation through the aortic sinus of valsalva to treat LVOT tachycardia.

METHODS

In seven patients (four males, one with valvular cardiomyopathy, six patients without heart disease) with sustained and non-sustained ventricular tachycardia (VT) an epicardial focus of LVOT tachycardia could be identified by pace-mapping and earliest local activation within the aortic sinus of valsalva. Coronary angiography served to define the position of the coronary arteries with respect to the ablation catheter. High frequency current was delivered using a closed-loop cooled tip catheter system (Chilli Cool(R), Boston Scientific). ECG, Holter-ECG, echocardiography and transesophageal echocardiography were performed after the procedure and 3 months later.

RESULTS

Foci were located in the left (two patients), in the right (three) and in the a coronary aortic sinus (two). Successful ablation could be achieved in six patients. No procedure-related complications could be observed during a mean follow-up of 4.2 months.

CONCLUSION

Monomorphic VT with epicardial origin in the LVOT can be successfully treated by cooled tip ablation through the aortic sinus of valsalva. The use of a cooled tip ablation system may be favourable in several ways: 1) it allows the creation of deep lesions necessary to reach remote foci; 2) due to lower temperatures at the catheter/tissue interface surface tissue damage may be reduced; 3) lower catheter temperature may additionally reduce the risk of local clot formation which is crucial for all left-sided procedures and especially for ablation in the sinus of valsalva.

摘要

背景

起源于左心室流出道(LVOT)的心外膜心律失常灶的单形性心动过速通常不能通过心内膜途径进行消融。我们描述了通过主动脉瓣窦使用冷盐水灌注导管消融治疗LVOT心动过速。

方法

在7例患者(4例男性,1例患有瓣膜性心肌病,6例无心脏病)中,持续性和非持续性室性心动过速(VT)的LVOT心动过速的心外膜灶可通过起搏标测和主动脉瓣窦内最早的局部激动来确定。冠状动脉造影用于确定冠状动脉相对于消融导管的位置。使用闭环冷盐水灌注导管系统(Chilli Cool™,波士顿科学公司)输送高频电流。术后及3个月后进行心电图、动态心电图、超声心动图和经食管超声心动图检查。

结果

病灶位于左侧(2例患者)、右侧(3例)和冠状动脉主动脉窦(2例)。6例患者成功消融。平均随访4.2个月期间未观察到与手术相关的并发症。

结论

起源于LVOT的心外膜单形性VT可通过经主动脉瓣窦冷盐水灌注消融成功治疗。使用冷盐水灌注消融系统可能在几个方面具有优势:1)它允许产生到达远处病灶所需的深部病变;2)由于导管/组织界面温度较低,可能减少表面组织损伤;3)较低的导管温度还可能降低局部血栓形成的风险,这对于所有左侧手术尤其是主动脉瓣窦内消融至关重要。

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