Gershbein Abbey B, Fuchs Gerhard J
Endourology Institute, Cedars Sinai Medical Center, 8635 W. 3rd Street, Suite 1070, Los Angeles, CA 90048, USA.
J Endourol. 2002 Sep;16(7):509-13. doi: 10.1089/089277902760367476.
Laparoscopic nephrectomy may make kidney donation more attractive. Modifications such as hand assistance may improve surgical outcomes. We compared our initial experience with hand-assisted laparoscopic nephrectomy with that of the conventional laparoscopic technique.
Two series of similar patients underwent conventional laparoscopic donor nephrectomy (LDN; N = 15) or hand-assisted laparoscopic donor nephrectomy (HLDN; N = 29). Operative time, warm ischemia time, estimated blood loss, complications, analgesic use, postoperative recovery, and serum creatinine concentration were compared.
Open conversion was required in one HLDN patient because of intra-abdominal adhesions, and this patient was excluded from further analysis. The operative time, time to kidney extraction, and warm ischemia time were significantly shorter in the HLDN group, averaging 204.8 v 275.7 minutes, 173.4 v 239.3 minutes, and 2 minutes 21 seconds v 3 minutes 45 seconds, respectively. The intraoperative complication rates were 3.6% and 13.3%, respectively (P = 0.07). The postoperative complication rates were 6.8% and 6.7%. All grafts were functioning at the end of the study period, and there were no differences in rejection episodes, need for dialysis, complications, or nadir creatinine concentration according to the method of harvest.
Hand-assisted laparoscopic donor nephrectomy provides shorter operative and warm ischemia times without a significant increase in donor morbidity.
腹腔镜肾切除术可能会使肾脏捐赠更具吸引力。诸如手辅助等改良方法可能会改善手术效果。我们将手辅助腹腔镜肾切除术的初步经验与传统腹腔镜技术的经验进行了比较。
两组相似患者分别接受了传统腹腔镜供体肾切除术(LDN;n = 15)或手辅助腹腔镜供体肾切除术(HLDN;n = 29)。比较了手术时间、热缺血时间、估计失血量、并发症、镇痛药物使用情况、术后恢复情况以及血清肌酐浓度。
1例HLDN患者因腹腔粘连需要转为开放手术,该患者被排除在进一步分析之外。HLDN组的手术时间、肾脏取出时间和热缺血时间明显更短,平均分别为204.8对275.7分钟、173.4对239.3分钟以及2分21秒对3分45秒。术中并发症发生率分别为3.6%和13.3%(P = 0.07)。术后并发症发生率分别为6.8%和6.7%。在研究期末所有移植物均功能良好,根据获取方法,在排斥反应发作、透析需求、并发症或最低肌酐浓度方面无差异。
手辅助腹腔镜供体肾切除术可缩短手术时间和热缺血时间,且供体发病率无显著增加。