Shiga Kiyoto, Tateda Masaru, Saijo Shigeru, Yokoyama Junkichi
Department of Head and Neck Surgery, Miyagi Cancer Center, Miyagi.
Nihon Jibiinkoka Gakkai Kaiho. 2002 Sep;105(9):937-40. doi: 10.3950/jibiinkoka.105.937.
Epithelioid hemangioendothelioma is an extremely rare, difficult-to-diagnose vascular tumor mainly originating from the lung or liver. Primary tumors in the head and neck are very rare. A 40-year-old man admitted for right throat pain had been found in biopsy elsewhere to have squamous cell carcinoma. Based on a diagnosis of mesopharyngeal cancer, he underwent radical surgery, reporting cough, sputum, and hemosputum postoperatively. Epithelioid hemangioendothelioma was first diagnosed histopathologically from a biopsy of scalp tumors. Lung specimens at open biopsy 4 years earlier showed the same histological features indicating he had had epithelioid hemangioendothelioma lesion since that time. We assumed this epithelioid hemangioendothelioma had originated in the lung and metastasized to the right tonsil. These tumors are typically progressive and aggressive, and this patient had a poor prognosis. We discuss tumor features and review them clinically and histologically.
上皮样血管内皮瘤是一种极其罕见、难以诊断的血管肿瘤,主要起源于肺或肝脏。头颈部的原发性肿瘤非常罕见。一名因右侧咽痛入院的40岁男性,在其他地方活检时被发现患有鳞状细胞癌。基于中咽癌的诊断,他接受了根治性手术,术后出现咳嗽、咳痰和咯血。上皮样血管内皮瘤最初是通过头皮肿瘤活检进行组织病理学诊断的。4年前开放活检时的肺标本显示出相同的组织学特征,表明他从那时起就患有上皮样血管内皮瘤病变。我们推测这种上皮样血管内皮瘤起源于肺并转移至右侧扁桃体。这些肿瘤通常呈进行性且具有侵袭性,该患者预后较差。我们讨论肿瘤特征并从临床和组织学方面进行回顾。