Tönz O
Schweiz Med Wochenschr. 1975 Nov 15;105(46):1543-7.
The neonatal thrombocytopenias (TP) can be classified into congenital (i.e. inherited), connatal (i.e. acquired in utero), perinatal and postnatal forms. In the following survey, only the perinatal TP are considered in detail. These arise from transit of immune antibodies or coagulation-activating material across the placenta or from hypoxia due to placental insufficiency. The auto- and isoimmune TP are illustrated by relevant clinical observations. The existence of a platelet deficiency is not a rarity in newborns or in high-risk infants. If is often an important leading symptom for a side range of different conditions.
新生儿血小板减少症(TP)可分为先天性(即遗传性)、出生时获得性(即在子宫内获得)、围生期和出生后形式。在以下调查中,仅详细考虑围生期TP。这些情况源于免疫抗体或凝血激活物质通过胎盘转移,或源于胎盘功能不全导致的缺氧。自身免疫性和同种免疫性TP通过相关临床观察得以说明。血小板缺乏在新生儿或高危婴儿中并不罕见。它常常是一系列不同病症的重要主要症状。