van Loenhout-Rooyacke J H, Sebek M M G G, Verbeek A L M
Municipal Health Service (GGD Regio Nijmegen), The Netherlands.
Neth J Med. 2002 Aug;60(7):281-4.
The diagnosis of tuberculosis in asylum seekers is followed by contact tracing, which is routinely performed by the Municipal Health Service (MHS). We investigated cases of tuberculosis whose symptoms became apparent after closure of regular contact tracing.
Analysis of data from the DNA Fingerprinting Surveillance Project on all Mycobacterium tuberculosis isolates and contact tracing instances.
Four additional cases of tuberculosis were detected, caused by bacteria of identical DNA fingerprints. No further contacts with a bacteriologically confirmed form of tuberculosis were found around these four new patients.
DNA fingerprinting contributed to tracing instances of late manifestations of tuberculosis transmission.
寻求庇护者的结核病诊断之后是接触者追踪,这通常由市卫生服务机构(MHS)进行。我们调查了在常规接触者追踪结束后症状才显现的结核病病例。
对来自DNA指纹监测项目的所有结核分枝杆菌分离株和接触者追踪实例的数据进行分析。
检测到另外4例结核病病例,由具有相同DNA指纹的细菌引起。在这4名新患者周围未发现与经细菌学确诊的结核病形式有进一步接触的情况。
DNA指纹有助于追踪结核病传播的晚期表现实例。