Oliveira Eduardo A, Silva Ana Cristina Simões, Rabelo Eli Armando Siqueira, Filgueiras F Freire, Pereira Alamanda K, Mesquita Francesca M
Pediatric Nephrourology Unit, Department of Pediatrics, Hospital das Clínicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Pediatr Nephrol. 2002 Nov;17(11):954-8. doi: 10.1007/s00467-002-0905-3. Epub 2002 Oct 8.
We report a case of transitory hypertension associated with unilateral multicystic dysplastic kidney (MCDK). A newborn girl with MCDK, detected by prenatal ultrasonography, was conservatively treated and has been followed for 18 months at the Pediatric Nephrourology Unit (HC-Belo Horizonte, Brazil). Arterial hypertension was observed at about 4 months of age and was associated with high levels of plasma renin activity and circulating angiotensin, and also with changes in renal Doppler ultrasonography. For these reasons, a nephrectomy was initially proposed. However, a spontaneous improvement of blood pressure levels was noticed at about 10 months of age. Serial Doppler ultrasonography showed involution of the affected renal volume and decreased arterial flow. The anatomical improvement was observed simultaneously with normalization of the peripheral renin and angiotensin values. The literature is reviewed regarding the relationship between hypertension and MCDK.
我们报告一例与单侧多囊性发育不良肾(MCDK)相关的暂时性高血压病例。一名通过产前超声检查发现患有MCDK的新生女婴接受了保守治疗,并在巴西贝洛奥里藏特市医院儿科肾病科接受了18个月的随访。在约4个月大时观察到动脉高血压,其与血浆肾素活性和循环血管紧张素水平升高以及肾脏多普勒超声检查的变化有关。基于这些原因,最初建议进行肾切除术。然而,在约10个月大时注意到血压水平自发改善。系列多普勒超声检查显示患侧肾脏体积缩小,动脉血流减少。在周围肾素和血管紧张素值恢复正常的同时观察到解剖学上的改善。本文对高血压与MCDK之间的关系进行了文献综述。