Guillem Philippe, Vlaeminck-Guillem Virginie, Leteurtre Emmanuelle, Kornhauser Richard, Cortot Antoine, Wemeau Jean-Louis, Triboulet Jean-Pierre
Service de Chirurgie Digestive et Générale, CHRU de Lille, France.
Gastroenterol Clin Biol. 2002 Aug-Sep;26(8-9):782-5.
We report two cases of fundic endocrine tumors associated with fundic atrophic gastritis-related hypergastrinemia and treated by antrectomy. About twenty infracentimetric tumors were observed in each patient and restrictively involved fundic mucosa. Antrectomy induced normalization of gastrinemia and the disappearance of fundic tumors, as soon as the 4(th) and 7(th) month. No recurrence was observed during the 5-year and 18-month follow-up time, respectively. We therefore consider that antrectomy may be regarded as a useful alternative treatment in the management of atrophic gastritis-related fundic endocrine tumors.
我们报告了两例与胃体萎缩性胃炎相关的高胃泌素血症相关的胃体内分泌肿瘤,并通过胃窦切除术进行治疗。每位患者均观察到约20个小于1厘米的肿瘤,且仅累及胃体黏膜。胃窦切除术后,分别在第4个月和第7个月时,胃泌素血症恢复正常,胃体肿瘤消失。在分别为期5年和18个月的随访期内均未观察到复发。因此,我们认为胃窦切除术可被视为治疗与萎缩性胃炎相关的胃体内分泌肿瘤的一种有效替代疗法。