Kabbash Christina, Laude Teresita A, Weinberg Jeffrey M, Silverberg Nanette B
Department of Dermatology, St Luke's-Roosevelt Hospital Center, New York, New York 10025, USA.
Pediatr Dermatol. 2002 Nov-Dec;19(6):541-5. doi: 10.1046/j.1525-1470.2002.00229.x.
We describe three adolescents with eruptive linear lesions of the back, abdomen, and extremities distributed along the lines of Blaschko. Clinically one of these lesions resembled an epidermal nevus in its morphology and distribution. A biopsy specimen demonstrated the typical histology of lichen planus (LP). There have been fewer than 20 reported cases of childhood linear LP. Our patients demonstrate that linear LP sometimes may closely resemble an epidermal nevus and may auger the onset of more generalized LP or more involvement along the lines of Blaschko, that is, "Blaschkoian" disease. Previous studies have referred to this variant as zosteriform. Our cases are the fourth, fifth, and sixth cases of childhood LP reported to occur along the lines of Blaschko. Based on the clinical findings in our patients and a review of the English-language literature, we believe that linear LP is usually distributed along the lines of Blaschko and should be renamed lichen planus, Blaschko subtype.
我们描述了三名青少年,其背部、腹部和四肢出现沿Blaschko线分布的爆发性线性损害。临床上,其中一处损害在形态和分布上类似表皮痣。活检标本显示为扁平苔藓(LP)的典型组织学表现。儿童期线状LP的报道病例少于20例。我们的患者表明,线状LP有时可能与表皮痣极为相似,并且可能预示着更广泛的LP发病或沿Blaschko线出现更多损害,即“Blaschko病”。既往研究将此变异型称为带状疱疹样。我们的病例是报道的第四、第五和第六例沿Blaschko线发生的儿童期LP。基于我们患者的临床发现以及对英文文献的回顾,我们认为线状LP通常沿Blaschko线分布,应重新命名为扁平苔藓,Blaschko亚型。