Baird Aisling, Green Tana, King Helen, Kinghorn George, Kudesia Goura
Central Health Clinic, Sheffield, UK.
J Fam Plann Reprod Health Care. 2002 Oct;28(4):215-7. doi: 10.1783/147118902101196658.
Chlamydia trachomatis is the most common bacterial sexually transmitted infection. Rates are highest in the 16-24-year-old age group. Untreated it can be a significant cause of morbidity. At least 50% of men and 70% of women with C. trachomatis are asymptomatic.
The aims of the study were: To determine the prevalence of C. trachomatis. To determine the success of our referral policy to genitourinary medicine (GU clinic). To determine the characteristics of the population with C. trachomatis. To estimate the level of recognition of 'chlamydia' as a concept.
Attendees at our youth clinic between October 2001 and March 2002.
Ethical approval was obtained for this ongoing study. All attendees who were sexually active were asked to participate. An information leaflet was provided. Those who agreed to participate answered a questionnaire, which included a number of lifestyle questions, and provided a urine sample for C. trachomatis testing using a strand displacement assay. Positive results were forwarded to the GU clinic, which provided antibiotic therapy, contact tracing and follow-up.
The ongoing study has yielded 616 results with 73 positive (11.9%). To date 66 individuals (90%) have attended the GU clinic and 41 (50%) of the possible 82 partners have responded to contact tracing.
Initial results show a high prevalence of C. trachomatis. There is a low condom usage despite a reasonable level of awareness of 'chlamydia'. Contact tracing has not been as successful as anticipated. When the study is complete, various service provision questions will need to be answered, such as the ability to treat the disease in a dedicated youth clinic, making urine testing for C. trachomatis by strand displacement assay (SDA) more widespread, the problem of follow-up, screening for associated sexually transmitted infections (STIs) and contact tracing in a relatively less mobile and less empowered population.
沙眼衣原体是最常见的细菌性性传播感染。发病率在16至24岁年龄组中最高。未经治疗，它可能是发病的一个重要原因。至少50%的感染沙眼衣原体的男性和70%的女性没有症状。
该研究的目的是：确定沙眼衣原体的患病率。确定我们转诊至泌尿生殖医学科（泌尿生殖诊所）政策的成效。确定感染沙眼衣原体人群的特征。估计对“衣原体”这一概念的认知水平。
2001年10月至2002年3月期间在我们青少年诊所就诊的患者。
这项正在进行的研究获得了伦理批准。所有性活跃的就诊者都被邀请参与。提供了一份信息传单。同意参与的人回答了一份问卷，其中包括一些生活方式问题，并提供一份尿液样本，使用链置换分析法进行沙眼衣原体检测。阳性结果被转至泌尿生殖诊所，该诊所提供抗生素治疗、接触者追踪和随访。
这项正在进行的研究已得出616份结果，其中73份为阳性（11.9%）。到目前为止，66人（90%）已前往泌尿生殖诊所就诊，在可能的82名性伴侣中，有41人（50%）对接触者追踪做出了回应。
初步结果显示沙眼衣原体患病率较高。尽管对“衣原体”有一定程度的认知，但避孕套使用率较低。接触者追踪没有预期的那么成功。当研究完成时，需要回答各种服务提供方面的问题，例如在专门的青少年诊所治疗该疾病的能力、使链置换分析法（SDA）用于沙眼衣原体尿液检测更为普及、随访问题、对相关性传播感染的筛查以及在流动性相对较小且权力相对较弱的人群中进行接触者追踪等问题。
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