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葡萄球菌菌血症与六氯酚沐浴。新生儿保育室中的流行情况。

Staphylococcal bacteremia and hexachlorophene bathing. Epidemic in a newborn nursery.

作者信息

Hyams P J, Counts G W, Monkus E, Feldman R, Kicklighter L, Gonzalez C

出版信息

Am J Dis Child. 1975 May;129(5):595-9. doi: 10.1001/archpedi.1975.02120420041015.

Abstract

An outbreak of staphylococcal bacteremia in healthy, full-term neonates occurred in the newborn nursery at a large county hospital not employing prophylactic hexachlorophene bathing. Seven infants had staphylococcal bacteremia and one had omphalitis. Two of the three isolates obtained for phage typing were type 86, and the other was 3c/71. Staphylococcal colonization rate in the nursery was 64% when the outbreak was recognized; 86% of these isolates were type 86. No predominant phage type was isolated from nursery personnel. The outbreak followed a six-month preliminary study that showed a rise in staphylococcal colonization rate from 2.2% with hexachlorophene bathing to 67% with a nonhexachlorophene-containing preparation. In a community survey of infants born during the two months prior to the epidemic, seven of eight babies with lesions were infected with Staphylococcus aureus type 86.

摘要

在一家未采用六氯酚预防性沐浴的大型县医院的新生儿病房,健康足月新生儿中爆发了葡萄球菌菌血症。7名婴儿患有葡萄球菌菌血症,1名患有脐炎。用于噬菌体分型的3株分离菌中,2株为86型,另1株为3c/71型。确认爆发时,病房内葡萄球菌定植率为64%;其中86%的分离株为86型。未从病房工作人员中分离出优势噬菌体类型。此次爆发之前进行了为期6个月的初步研究,结果显示葡萄球菌定植率从使用六氯酚沐浴时的2.2%升至使用不含六氯酚制剂时的67%。在对疫情前两个月出生的婴儿进行的社区调查中,8名有皮损的婴儿中有7名感染了86型金黄色葡萄球菌。

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