Gérard J L, Desgranges P, Becquemin J P, Desse H, Mellière D
Service de Chirurgie Vasculaire, CHU Henri Mondor, 94010 Créteil (Paris XII), France.
J Mal Vasc. 2002 Oct;27(4):222-5.
The purpose of this feasibility study was to demonstrate that endovenous laser can be a useful alternative to conventional surgery for ambulatory treatment of advanced varicose veins. We assessed an open, non-randomized series of patients treated in one center by the same operator. The study protocol was approved by the local ethics committee. Twenty patients with stage II or III varicose veins in the Porter classification gave their informed consent to participate in the study. The patients were treated with endovenous laser by the first author in the outpatient clinic of the Henri Mondor University Hospital vascular surgery department. All procedures were conducted under local anesthesia. A 980 nm laser diode optic fiber was introduced into the vein percutaneously. Laser beams were fired from the sapheno-femoral junction to just under the genu, withdrawing the fiber 3 mm every 1.5 sec. Clinical evaluation with a quality-of-life questionnaire and duplex-scan was performed at days 3, 8 and 30 post-op. Complete occlusion and retraction of the treated vein was observed at day 3 and 30, from the point of introduction to the sapheno-femoral junction in 18 of the 20 patients. The branches of the greater saphenous vein remained patent with physiological flow in the stump which remained patent 1 to 2 cm upstream from the sapheno-femoral junction. The length of the patent stump dependend on the level of the anterior or posterior branch. There were no adverse effects related to the local anesthesia. Pain was low to mild during treatment and the days following the procedure, requiring 8 tablets of acetominophen at most. Hematomas were minimal and had completely resolved by the end of the first month. No work stoppage was required for the 14 patients with occupational activities. There were no cases of deep or superficial vein thrombosis. Complete occlusion and retraction of the varicose vein at one month suggests this treatment has a long-lasting effect. Long-term evaluation is required. Treatment of advanced varicose veins with endovenous laser can be an alternative to surgical treatment providing the advantage of outpatient ambulatory treatment.
本可行性研究的目的是证明,对于晚期静脉曲张的门诊治疗,静脉内激光治疗可成为传统手术的一种有效替代方法。我们评估了在一个中心由同一名操作者治疗的一组开放、非随机的患者。研究方案已获当地伦理委员会批准。20例波特分类为II期或III期静脉曲张的患者已签署知情同意书参与本研究。这些患者在亨利·蒙多大学医院血管外科门诊由第一作者进行静脉内激光治疗。所有手术均在局部麻醉下进行。一根980纳米激光二极管光纤经皮插入静脉。激光束从隐股交界处发射至膝下,每1.5秒将光纤回撤3毫米。术后第3天、第8天和第30天,采用生活质量问卷和双功超声扫描进行临床评估。在第3天和第30天,20例患者中有18例从隐股交界处的导入点观察到治疗静脉完全闭塞和回缩。大隐静脉分支保持通畅,残端有生理性血流,在隐股交界处上游1至2厘米处保持通畅。残端通畅的长度取决于前支或后支的水平。未出现与局部麻醉相关的不良反应。治疗期间及术后数天疼痛轻微,最多需要8片对乙酰氨基酚。血肿极小,在第一个月末已完全消退。14例有职业活动的患者无需停工。未出现深静脉或浅静脉血栓形成的病例。一个月时静脉曲张完全闭塞和回缩表明该治疗具有持久效果。需要进行长期评估。静脉内激光治疗晚期静脉曲张可作为手术治疗的替代方法,具有门诊治疗的优势。