Umriukhin P E
P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow.
Bull Exp Biol Med. 2002 Jul;134(1):5-7. doi: 10.1023/a:1020679815690.
Microiontophoresis of delta sleep-inducing peptide primarily activated neurons in the dorsal hippocampus, anteroventral thalamic nucleus, lateral hypothalamus, and sensorimotor cortex. Microiontophoretic administration of glutamate markedly enhanced neuronal activity, while preliminary microionophoresis of delta sleep-inducing peptide blocked the excitatory effect of glutamate on neurons in these brain structures.
δ-睡眠诱导肽的微量离子电渗主要激活了背侧海马体、丘脑前腹核、下丘脑外侧和感觉运动皮层中的神经元。谷氨酸的微量离子电渗给药显著增强了神经元活动，而预先进行δ-睡眠诱导肽的微量离子电渗则阻断了谷氨酸对这些脑结构中神经元的兴奋作用。
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