Raobijaona H, Randrianotahina C H, Razanamparany M
Hôpital général de Befelatanana, Centre Hospitalier Universitaire d'Antananarivo, BP 8394-101 Antananarivo-Madagascar.
Arch Inst Pasteur Madagascar. 2000;66(1-2):23-5.
The definition of severe malaria is no longer limited to cerebral malaria, but it is as well extended to other clinical forms of the disease. The authors reported the epidemiological and clinical survey and evaluative aspects of severe malaria in Antananarivo. This retrospective study included 48 children less than 15 years old, hospitalized at the paediatric unit Debré of the Centre Hospitalier Universitaire de Befelatanana (Antananarivo) for severe malaria as defined by world Health Organization (WHO) criteria. The hospitalization frequency was 0.87%. Higher frequency was noticed for the children less than 5 years old, the sex-ratio was 1.4/1. The cerebral complications as seen in many African countries were the most frequent clinical form. The death rate was 14.58% and the proportional mortality was 1.07%, 2.1% of the patients had sequel. The improvement of severe malaria prognosis was not only on better equipment in intensive care wards, but also on improved and early diagnosis and management.
重症疟疾的定义不再局限于脑型疟疾,而是还扩展到了该疾病的其他临床形式。作者报告了塔那那利佛重症疟疾的流行病学、临床调查及评估情况。这项回顾性研究纳入了48名15岁以下儿童,他们因符合世界卫生组织(WHO)标准定义的重症疟疾,在贝费拉塔纳纳大学中心医院(塔那那利佛)的儿科德布雷病房住院。住院频率为0.87%。5岁以下儿童的频率更高,男女比例为1.4/1。正如在许多非洲国家所见到的,脑型并发症是最常见的临床形式。死亡率为14.58%,比例死亡率为1.07%,2.1%的患者有后遗症。重症疟疾预后的改善不仅在于重症监护病房设备的改善,还在于诊断和管理的改进及早期进行。