幼年特发性关节炎患儿的有氧适能：一项系统评价
Aerobic fitness in children with juvenile idiopathic arthritis: a systematic review.
作者信息
Takken Tim, Hemel Arlette, van der Net Janjaap, Helders Paul J M
机构信息
Department of Pediatric Physical Therapy, University Hospital for Children and Youth Het Wilhelmina Kinderziekenhuis, Utrecht, The Netherlands.
出版信息
J Rheumatol. 2002 Dec;29(12):2643-7.
OBJECTIVE
To determine whether children with juvenile idiopathic arthritis (JIA) have lower physical fitness compared to healthy children, and to determine the clinical relevance of this impairment.
METHODS
A systematic literature search was performed using MEDLINE, CINAHL, EMBASE and SPORTDiscus. The appropriate titles were identified and the data were extracted from these publications. The maximal oxygen consumption (VO2peak; in ml.kg-1.min-1) during a maximal exercise test until volitional exhaustion was used as the main outcome for this review.
RESULTS
Nine studies were identified in the literature. Data from 5 studies (144 patients) were pooled in a metaanalysis. The VO2peak of the patients with JIA was 21.8% (95% CI 13.7, 29.9) lower than that of healthy children (p < 0.0001).
CONCLUSION
The results of the metaanalysis suggest that children with JIA have moderate to heavy impairment in physical fitness as represented by maximal oxygen consumption compared to healthy children.
目的
确定与健康儿童相比，幼年特发性关节炎（JIA）患儿的体能是否较低，并确定这种损害的临床相关性。
方法
使用MEDLINE、CINAHL、EMBASE和SPORTDiscus进行系统的文献检索。识别出合适的标题，并从这些出版物中提取数据。将最大运动试验直至自愿疲劳时的最大耗氧量（VO2peak；单位为ml.kg-1.min-1）用作本次综述的主要结果。
结果
文献中识别出9项研究。5项研究（144例患者）的数据被纳入荟萃分析。JIA患儿的VO2peak比健康儿童低21.8%（95%CI 13.7，29.9）（p<0.0001）。
结论
荟萃分析结果表明，与健康儿童相比，JIA患儿在以最大耗氧量表示的体能方面存在中度至重度损害。
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