Zhao Wei, Cure Joel, Castro Claudia Y
Departments of Pathology and Radiology, University of Alabama at Birmingham, AL 35249, USA.
Ann Diagn Pathol. 2002 Dec;6(6):373-7. doi: 10.1053/adpa.2002.36656.
We describe a case of low-grade osteosarcoma of the jaw. The patient is a 25-year-old woman who presented with large, nontender, slowly progressive, expansile left mandibular mass. X-ray showed a predominantly hypodense mass with erosive growth pattern affecting the angle, posterior body, and ramus of the left mandible. The patient underwent left hemimandibulectomy. The tumor was a white-tan, well-circumscribed, multinodular, firm mass that measure 7.0 cm. Microscopically, the tumor was composed of bland spindle cells, with minimal cellular atypia, absent mitotic figures, very focal osteoid formation with extensive bone destruction, and soft tissue infiltration. Immunhistochemical stains for a large panel of antibodies were noncontributory. At present the patient is alive and well 7 months after surgery.
我们描述了一例下颌骨低度骨肉瘤病例。患者为一名25岁女性，表现为左侧下颌骨有一个较大、无压痛、缓慢进展、呈膨胀性生长的肿块。X线显示主要为低密度肿块，呈侵蚀性生长模式，累及左侧下颌骨的角部、体后部及升支。患者接受了左侧半下颌骨切除术。肿瘤为灰白色、边界清楚、多结节状、质地坚实的肿块，大小为7.0 cm。显微镜下，肿瘤由形态温和的梭形细胞组成，细胞异型性极小，无核分裂象，仅有局灶性骨样组织形成，伴有广泛的骨质破坏及软组织浸润。一大组抗体的免疫组化染色结果无诊断意义。目前患者术后7个月，状态良好。
