Farrell April L, Warshaw Erin M, Zhao Yanli, Nelson David
University of Minnesota Medical School, The Department of Dermatology, University of Minnesota, Minneapolis VA Medical Center, Minneapolis, MN, USA.
Am J Contact Dermat. 2002 Dec;13(4):183-9. doi: 10.1053/ajcd.2002.36636.
Natural rubber latex allergy is a potentially life-threatening, Type I, immediate allergic reaction. Despite great strides in identification of high-risk groups, methods for diagnosis remain limited in the United States.
The objective of this study was to estimate the prevalence of evaluation for latex allergy and methodologies used by allergists in the United States.
A cross-sectional survey of all US Fellows of the American Academy of Allergy, Asthma and Immunology was conducted.
Of 1,239 questionnaires mailed, 519 (42%) were returned. Ninety-five percent of responding allergists reported evaluating patients for latex allergy. RAST and skin prick testing were the most commonly used tests. Sixty-two percent of respondents reported performing prick testing for latex allergy, with those in academic practices significantly more likely to do so. Whereas respondents practicing in the Northern United States were significantly more likely to evaluate for latex allergy than those in the Southern United States, no associations were found between practice location and prick testing for latex allergy. There was no association between practice type and evaluation for latex allergy. Only 6% of allergists reported ever witnessing a patient with anaphylaxis during latex allergy testing.
Almost all responding allergists evaluated patients for latex allergy, with approximately two thirds utilizing prick testing.
天然橡胶乳胶过敏是一种可能危及生命的I型速发型过敏反应。尽管在识别高危人群方面取得了很大进展,但在美国,诊断方法仍然有限。
本研究的目的是评估美国过敏症专科医生对乳胶过敏进行评估的患病率以及所使用的方法。
对美国过敏、哮喘与免疫学会的所有会员进行了横断面调查。
在邮寄的1239份问卷中,有519份(42%)被退回。95%的回复过敏症专科医生报告对患者进行了乳胶过敏评估。放射性变应原吸附试验(RAST)和皮肤点刺试验是最常用的检测方法。62%的受访者报告对乳胶过敏进行点刺试验,学术机构的受访者进行该试验的可能性显著更高。美国北部的受访者对乳胶过敏进行评估的可能性显著高于美国南部的受访者,但在乳胶过敏点刺试验与执业地点之间未发现关联。执业类型与乳胶过敏评估之间没有关联。只有6%的过敏症专科医生报告曾在乳胶过敏检测期间目睹患者发生过敏反应。
几乎所有回复的过敏症专科医生都对患者进行了乳胶过敏评估,约三分之二的医生使用点刺试验。