斜坡原发性B细胞淋巴瘤：病例报告
Primary B-cell lymphoma of the clivus: case report.
作者信息
Tsai Veling W, Rybak Leonard, Espinosa Jose, Kuhn Matthew J, Kamel Onsi W, Mathews Frances, Glatz F Robert
机构信息
Southern Illinois University School of Medicine, Springfield, Illinois, USA.
出版信息
Surg Neurol. 2002 Sep-Oct;58(3-4):246-50. doi: 10.1016/s0090-3019(02)00845-5.
BACKGROUND
Lymphomas usually present in extranodal sites late in the course of the disease. Moreover, it is uncommon for a primary non-Hodgkin's lymphoma to present with cranial nerve palsies; reports in the literature are rare.
CASE DESCRIPTION
We report the case of a 60-year-old woman with complaints of headache and double vision. MRI revealed an expansive clival lesion without pituitary invasion. An endoscopic transsphenoidal procedure was performed for diagnosis and partial resection of the mass.
CONCLUSION
Primary diffuse large B-cell lymphoma of the clivus is rare. An endoscopic transsphenoidal approach to the skull base is described, along with characteristic clinical, radiologic, and pathologic findings of the lesions.
背景
淋巴瘤通常在疾病晚期出现于结外部位。此外，原发性非霍奇金淋巴瘤出现颅神经麻痹的情况并不常见；文献报道很少。
病例描述
我们报告一例60岁女性，主诉头痛和复视。磁共振成像（MRI）显示斜坡有一占位性病变，未侵犯垂体。为明确诊断及部分切除肿块，实施了内镜经蝶窦手术。
结论
斜坡原发性弥漫性大B细胞淋巴瘤罕见。本文描述了一种经蝶窦入路至颅底的内镜手术方法，以及该病变的特征性临床、影像学和病理学表现。
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