Maguire Eleanor A, Valentine Elizabeth R, Wilding John M, Kapur Narinder
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.
Nat Neurosci. 2003 Jan;6(1):90-5. doi: 10.1038/nn988.
Why do some people have superior memory capabilities? We addressed this age-old question by examining individuals renowned for outstanding memory feats in forums such as the World Memory Championships. Using neuropsychological measures, as well as structural and functional brain imaging, we found that superior memory was not driven by exceptional intellectual ability or structural brain differences. Rather, we found that superior memorizers used a spatial learning strategy, engaging brain regions such as the hippocampus that are critical for memory and for spatial memory in particular. These results illustrate how functional neuroimaging might prove valuable in delineating the neural substrates of mnemonic techniques, which could broaden the scope for memory improvement in the general population and the memory-impaired.
为什么有些人拥有卓越的记忆能力?我们通过研究在诸如世界记忆锦标赛等论坛中因出色记忆壮举而闻名的个体,来探讨这个由来已久的问题。利用神经心理学测量方法以及大脑结构和功能成像,我们发现卓越的记忆力并非由超常的智力或大脑结构差异所驱动。相反,我们发现记忆超群者使用了一种空间学习策略,激活了诸如海马体等对记忆尤其是空间记忆至关重要的脑区。这些结果说明了功能性神经成像在描绘记忆技巧的神经基础方面可能具有的价值,这可能会拓宽普通人群和记忆受损者改善记忆的范围。