[腹腔内化疗对晚期Borrmann IV型胃癌的疗效]

[Efficacy of intraperitoneal chemotherapy for advanced Borrmann type IV gastric carcinoma].

作者信息

Akamo Yoshimi, Takeyama Hiromitsu, Funahashi Hitoshi, Yamamori Yoko, Yamamoto Minoru, Teranishi Futoshi, Manabe Tadao

机构信息

First Dept. of Surgery, Nagoya City University Medical School.

出版信息

Gan To Kagaku Ryoho. 2002 Nov;29(12):2184-7.

PMID:12484032

Abstract

We report four patients with advanced Borrmann type IV gastric carcinoma, in whom intraperitoneal chemotherapy with low-dose CDDP and 5-FU plus MMC via a peritoneal port was effective against peritoneal metastasis. However, none of the four patients survived for a long period. During treatment, they were followed on an outpatient basis and received intraperitoneal chemotherapy biweekly with good control of peritoneal metastasis. The ratio of the outpatient follow-up period was more than 50% in all these patients. Intraperitoneal chemotherapy may be effective for controlling peritoneal metastasis of advanced Borrmann type IV gastric carcinoma, and contribute to maintaining the patient's quality of life.

摘要

我们报告了4例晚期Borrmann IV型胃癌患者，通过腹膜置管给予低剂量顺铂、5-氟尿嘧啶联合丝裂霉素进行腹腔内化疗，对腹膜转移有效。然而，这4例患者均未长期存活。治疗期间，他们在门诊接受随访，每两周接受一次腹腔内化疗，腹膜转移得到良好控制。所有这些患者的门诊随访期比例均超过50%。腹腔内化疗可能对控制晚期Borrmann IV型胃癌的腹膜转移有效，并有助于维持患者的生活质量。