Fukunari Nobuhiro
Surgical branch of ITO Hospital, 4-3-6, Jingumae, Shibuya-ku, Tokyo 150-8308, Japan.
Biomed Pharmacother. 2002;56 Suppl 1:55s-59s. doi: 10.1016/s0753-3322(02)00213-5.
Recently, ultrasonography of the thyroid gland has proved to be a useful clinical diagnostic method. The newly developed high-resolution ultrasonography with color-Doppler flow mapping function can reveal fine details of the thyroid gland and the hemodynamic features of thyroid neoplasmas. Ultrasonography can deliver a diagnostic accuracy of over 90% in thyroid carcinoma, especially papillary carcinoma. However, in the case of follicular carcinoma, neither conventional B-mode ultrasound imaging nor aspiration biopsy cytology can deliver satisfactory results. Color-Doppler imaging examination of 212 follicular tumors has been carried out, resulting in the characteristic finding that a high-velocity pulsative blood flow penetrates the tumor in the case of follicular carcinoma, which led to new diagnostic criteria with color-Doppler examination. The differential diagnostic grading score using color-Doppler examination and FFT analysis can show a dramatic diagnostic accuracy of 81.0%, a sensitivity of 88.9% and a specificity of 74.2%. Ultrasound with the color-Doppler function can play a more important role in the differential diagnosis of thyroid tumors.
最近，甲状腺超声检查已被证明是一种有用的临床诊断方法。新开发的具有彩色多普勒血流成像功能的高分辨率超声检查可以揭示甲状腺的细微细节以及甲状腺肿瘤的血流动力学特征。超声检查对甲状腺癌，尤其是乳头状癌的诊断准确率超过90%。然而，对于滤泡状癌，传统的B超成像和细针穿刺活检细胞学检查均不能给出满意的结果。对212例滤泡状肿瘤进行了彩色多普勒成像检查，结果发现一个特征性表现，即滤泡状癌病例中有高速搏动血流穿入肿瘤，这导致了彩色多普勒检查的新诊断标准。使用彩色多普勒检查和FFT分析的鉴别诊断分级评分显示出显著的诊断准确率81.0%、敏感性88.9%和特异性74.2%。具有彩色多普勒功能的超声在甲状腺肿瘤的鉴别诊断中可以发挥更重要的作用。
