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Avasimibe Pfizer.

作者信息

Burnett John R, Huff Murray W

机构信息

Department of Core Clinical Pathology & Biochemistry, Division of Laboratory Medicine, Royal Perth Hospital, Wellington Street, Perth, WA 6847, Australia.

出版信息

Curr Opin Investig Drugs. 2002 Sep;3(9):1328-33.

Abstract

Avasimibe (also known as CI-1011 or PD-148515) is a selective acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitory lipid-regulating agent under development by Pfizer (formerly Parke-Davis) for the potential treatment of hyperlipidemia and atherosclerosis. The compound is currently undergoing phase III clinical trials [371470].

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