Roussel Martine F
Department of Genetics and Tumor Cell Biology, Danny Thomas Research Tower, 5006C, St Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA.
Cancer Cell. 2002 Dec;2(6):434-5. doi: 10.1016/s1535-6108(02)00216-7.
Increased p53 expression under the endogenous promoter protects "super p53" mice from tumorigenesis without the undesirable effects of premature aging.
在内源启动子作用下p53表达增加可保护“超级p53”小鼠免于肿瘤发生,且无早衰的不良影响。