四齿四棱草地上部分的化学成分

Chemical constituents of the aerial parts of Schnabelia tetradonta.

作者信息

Dou Hui, Zhou Yan, Chen Changxiang, Peng Shulin, Liao Xun, Ding Lisheng

机构信息

Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.

出版信息

J Nat Prod. 2002 Dec;65(12):1777-81. doi: 10.1021/np020233z.

DOI:10.1021/np020233z

PMID:12502313

Abstract

A phytochemical study on the ethanol extract of the aerial parts of Schnabelia tetradonta led to the isolation of five new compounds, 1-5, together with seven known compounds. The structures of the new compounds were elucidated on the basis of spectral data interpretation as 2alpha,3alpha,23,29-tetrahydroxyolean-12-en-28-oic acid (1), 3-O-beta-d-glucuronopyranosyl-2beta,3beta,16beta-trihydroxy-28-norolean-12-en-15-on-23-oic acid (2), 21-O-beta-d-glucopyranosyl-3beta,21alpha,30-trihydroxyolean-13(18)-en-24-oic acid (3), 6-C-beta-l-arabinopyranosyl-8-C-alpha-l-arabinopyranosylapigenin (4), and 4-acetylaminoethylphenyl 1-O-[6-O-(Z)-p-methoxycinnamoyl-beta-d-glucopyranosyl(1-->2)]-[beta-d-glucopyranosyl(1-->3)]-alpha-l-rhamnopyranoside (5), respectively.

摘要

对四齿四棱草地上部分乙醇提取物进行的植物化学研究，导致分离出5个新化合物1 - 5以及7个已知化合物。基于光谱数据解析，新化合物的结构分别被鉴定为2α,3α,23,29 - 四羟基齐墩果 - 12 - 烯 - 28 - 酸（1）、3 - O - β - D - 葡糖醛酸吡喃糖基 - 2β,3β,16β - 三羟基 - 28 - 降齐墩果 - 12 - 烯 - 15 - 酮 - 23 - 酸（2）、21 - O - β - D - 吡喃葡萄糖基 - 3β,21α,30 - 三羟基齐墩果 - 13(18) - 烯 - 24 - 酸（3）、6 - C - β - L - 阿拉伯吡喃糖基 - 8 - C - α - L - 阿拉伯吡喃糖基芹菜素（4）和4 - 乙酰氨基乙基苯基1 - O - [6 - O - (Z) - 对甲氧基肉桂酰 - β - D - 吡喃葡萄糖基(1→2)] - [β - D - 吡喃葡萄糖基(1→3)] - α - L - 鼠李吡喃糖苷（5）。