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预测催眠依赖性慢性失眠症心理治疗后的长期疗效。

Predicting longer-term outcomes following psychological treatment for hypnotic-dependent chronic insomnia.

作者信息

Morgan Kevin, Thompson Joanne, Dixon Simon, Tomeny Maureen, Mathers Nigel

机构信息

Department of Human Sciences, Loughborough University, Leicestershire LE11 3TU, UK.

出版信息

J Psychosom Res. 2003 Jan;54(1):21-9. doi: 10.1016/s0022-3999(02)00569-x.

Abstract

OBJECTIVES

To identify predictors of treatment adherence, patient dropout, and treatment response among long-term hypnotic users recruited into a randomized controlled trial of psychological treatment for insomnia.

METHODS

Of 108 treatment and 101 control patients initially recruited, 37 treatment group patients (34.3%) failed to complete all 6 sessions (i.e., were nonadherent), while across both groups 61 (29.2%) patients failed to return postal assessments at 3-month follow-up (i.e., dropped out). Relationships between baseline characteristics and adherence (adherent vs. nonadherent) and attrition (dropout vs. nondropout) were examined in discriminant models. Relationships between baseline characteristics and treatment response (sleep quality, sleep latency, sleep efficiency, and hypnotic drug use) were examined in a series of multiple regression models.

RESULTS

Adherent patients showed a significantly greater severity of pretreatment sleep disturbance, as measured by the Pittsburgh Sleep Quality Index (PSQI). Dropout at 3 months was associated with significantly lower perceived health status at baseline. In the regression models, lower Cure/Control subscale scores from the Illness Perception Questionnaire (IPQ) predicted greater posttreatment improvements in sleep efficiency and PSQI scores, while lower baseline anxiety scores predicted a posttreatment increase in hypnotic-free nights/week.

CONCLUSION

In routine clinical practice settings, higher anxiety and a less positive attitude towards symptom control were associated with poorer treatment response. Adherence and attrition show a different pattern of associations, with greater need (as indexed by insomnia severity) predicting higher levels of service uptake and poorer general health predicting a higher likelihood of dropout.

摘要

目的

在一项针对失眠的心理治疗随机对照试验中,确定长期使用催眠药物患者的治疗依从性、患者退出情况及治疗反应的预测因素。

方法

在最初招募的108名治疗组患者和101名对照组患者中,37名治疗组患者(34.3%)未完成全部6次治疗(即未依从),而两组共有61名(29.2%)患者在3个月随访时未回复邮寄评估(即退出)。在判别模型中检验基线特征与依从性(依从与不依从)和损耗(退出与未退出)之间的关系。在一系列多元回归模型中检验基线特征与治疗反应(睡眠质量、睡眠潜伏期、睡眠效率和催眠药物使用情况)之间的关系。

结果

根据匹兹堡睡眠质量指数(PSQI)测量,依从治疗的患者在治疗前睡眠障碍的严重程度显著更高。3个月时退出与基线时感知到的健康状况显著较低有关。在回归模型中,疾病感知问卷(IPQ)中较低的治愈/控制分量表得分预示着睡眠效率和PSQI得分在治疗后有更大改善,而较低的基线焦虑得分预示着治疗后每周无催眠药物的夜晚数增加。

结论

在常规临床实践环境中,较高的焦虑水平和对症状控制较消极的态度与较差的治疗反应相关。依从性和退出情况呈现出不同的关联模式,更高的需求(以失眠严重程度为指标)预示着更高的服务利用率,而较差的总体健康状况预示着更高的退出可能性。

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