Meo Sultan A, Azeem Muhammad A, Arian Shoukat A, Subhan Merza M
Department of Physiology, Hamdard College of Medicine and Dentistry, Hamdard University, Karachi, Pakistan.
Saudi Med J. 2002 Nov;23(11):1386-9.
Considering the hazards of exposure to cement dust, this study incorporated basic hematological parameters, erythrocyte sedimentation rate and the total leukocyte count. The idea was to identify a simple, readily available and cost effective screening test that could help in identifying the presence of disease, its severity, or both in cement mill workers potentially related to their work place.
This study was carried out in the Department of Physiology, Faculty of Health and Medical Sciences, Hamdard University, Karachi and the University of Karachi, Pakistan, during the time frame 1999-2000. In this study a group of 50, apparently healthy volunteers male cement mill workers were randomly selected with ages ranging from 20-60 years. They were matched with another group of 50, control healthy male subjects in terms of age, height, weight and socioeconomic status. Both groups met with exclusion criteria as per standard. The total leukocyte count was performed on an auto analyzer, (Symex-K-1000 CP-Analyzer, Japan) and the erythrocyte sedimentation rate was measured by Westergren tube method. Results were compared in a mean, and on the basis of, period of exposure in a cement mill.
In the present study, the mean values of erythrocyte sedimentation rate (p<0.05) and total leukocyte count (p<0.02) significantly increased, but the parameters do not revealing statistically significant differences between 2 groups on the basis of duration of exposure in a cement mill.
This study has shown that exposure to cement dust causes increased mean values of total leukocyte count and erythrocyte sedimentation rate. However, this change is not related to the duration of exposure in a cement mill.
考虑到接触水泥粉尘的危害,本研究纳入了基本血液学参数、红细胞沉降率和白细胞总数。目的是确定一种简单、易于获得且具有成本效益的筛查测试,以帮助识别疾病的存在、严重程度或两者,这些疾病可能与水泥厂工人的工作场所有关。
本研究于1999年至2000年期间在巴基斯坦卡拉奇哈姆达德大学健康与医学科学学院生理学系以及卡拉奇大学进行。在本研究中,随机选择了一组50名年龄在20至60岁之间、表面健康的男性水泥厂工人志愿者。他们在年龄、身高、体重和社会经济地位方面与另一组50名健康男性对照受试者相匹配。两组均符合标准排除标准。白细胞总数通过自动分析仪(日本Sysmex-K-1000 CP分析仪)进行检测,红细胞沉降率采用魏氏管法测量。根据水泥厂的暴露时间均值对结果进行比较。
在本研究中,红细胞沉降率(p<0.05)和白细胞总数(p<0.02)的均值显著升高,但根据在水泥厂的暴露时间,两组参数在统计学上没有显著差异。
本研究表明,接触水泥粉尘会导致白细胞总数和红细胞沉降率的均值升高。然而,这种变化与在水泥厂的暴露时间无关。