从氨基酸序列信息预测蛋白质亚细胞定位。
Predicting protein subcellular localisation from amino acid sequence information.
作者信息
Emanuelsson Olof
机构信息
Stockholm Bioinformatics Center, Stockholm University, Stockholm, Sweden.
出版信息
Brief Bioinform. 2002 Dec;3(4):361-76. doi: 10.1093/bib/3.4.361.
PMID:12511065
Abstract
Predicting the subcellular localisation of proteins is an important part of the elucidation of their functions and interactions. Here, the amino acid sequence motifs that direct proteins to their proper subcellular compartment are surveyed, different methods for localisation prediction are discussed, and some benchmarks for the more commonly used predictors are presented.
摘要
预测蛋白质的亚细胞定位是阐明其功能和相互作用的重要组成部分。本文综述了引导蛋白质进入其正确亚细胞区室的氨基酸序列基序，讨论了不同的定位预测方法，并给出了一些常用预测器的基准。
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