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[深低温下大鼠睾丸腺细胞的变化]

[Changes in rat testis glandulocytes under deep hypothermia].

作者信息

Blinova T S

出版信息

Arkh Anat Gistol Embriol. 1976 Jan;70(1):66-73.

PMID:1252141
Abstract

White mongrel rats weighing 180-220 g were daily cooled in water at 4-5 degrees C up to 21-23 degrees C in the rectum. The animals were killed on the 1, 5, 10, 15, 20 and 25th days of experiment. The total amount of glandulocytes counted per a cross section of the tubule did not change throughout the experiment. The total weight of pictures of 100 glandulocytes (taken randomly), obtained through a drawing apparatus on a standard paper was reliably decreased by 28%. By the end of the observation period the amount of degenerating glandulocytes increased 2 times and that of slightly active in a functional respect so-called "small" glandulocytes increased 4 times, while the number of active ("large") glandulocytes diminished approximately 1,5 times. The activity of SDG and ICDG in interstitial cells dropped by 26% and 18%. The activity of LDG was 52% greater. The G-6-PhDG activity was 40% greater while the activity of clue enzyme steroidgenase--3beta-OSD under hypothermia was inhibited by 36%.

摘要

体重为180 - 220克的白色杂种大鼠每天置于4 - 5摄氏度的水中冷却,直至直肠温度降至21 - 23摄氏度。在实验的第1、5、10、15、20和25天处死动物。在整个实验过程中,每个肾小管横截面上计数的腺细胞总数没有变化。通过绘图装置在标准纸上随机获取的100个腺细胞图片的总重量可靠地减少了28%。到观察期结束时,退化腺细胞的数量增加了2倍,功能上略有活性的所谓“小”腺细胞数量增加了4倍,而活跃(“大”)腺细胞的数量减少了约1.5倍。间质细胞中SDG和ICDG的活性分别下降了26%和18%。LDG的活性高52%。G - 6 - PhDG的活性高40%,而低温下线索酶类固醇生成酶——3β - OSD的活性受到36%的抑制。

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