腋窝I-II水平以外的前哨淋巴结与乳腺癌分期
Sentinel nodes outside level I-II of the axilla and staging in breast cancer.
作者信息
Rönka R, Krogerus L, Leppänen E, Smitten K V, Leidenius M
机构信息
Breast Surgery Unit, Maria Hospital, Helsinki University Hospital, Lapinlahdenkatu 16, 00029 HUS, Helsinki, Finland.
出版信息
Anticancer Res. 2002 Sep-Oct;22(5):3109-12.
BACKGROUND
The aim of the study was to evaluate the incidence of sentinel nodes and sentinel node metastases outside levels I-II of the axilla in breast cancer.
PATIENTS AND METHODS
Altogether 170 breast cancer patients with 172 clinically node-negative T1-T2 tumours underwent lymphoscintigraphy and were included in a prospective study.
RESULTS
The lymphoscintigraphy showed sentinel node(s) in the axilla in 150 (87%) breast cancer cases. Thirty (17%) patients had sentinel nodes outside the axilla. Lymphatic drainage solely outside the axilla was encountered in two patients. Lymph node metastases were found in the axilla in 40% and outside the axilla in 17% of the 30 patients with extra-axillary sentinel nodes. Two patients with sentinel node metastases outside the axilla had no axillary metastases.
CONCLUSION
The biopsy of sentinel nodes outside the axilla is a potential tool for more accurate staging in breast cancer, since it provides additional information as compared to axillary staging alone.
背景
本研究的目的是评估乳腺癌患者腋窝I-II水平以外前哨淋巴结及前哨淋巴结转移的发生率。
患者与方法
共有170例患有172个临床检查淋巴结阴性的T1-T2肿瘤的乳腺癌患者接受了淋巴闪烁显像检查，并纳入一项前瞻性研究。
结果
淋巴闪烁显像显示，150例（87%）乳腺癌患者腋窝存在前哨淋巴结。30例（17%）患者的前哨淋巴结位于腋窝以外。2例患者的淋巴引流仅在腋窝以外。在30例腋窝外有前哨淋巴结的患者中，40%的患者腋窝发现淋巴结转移，17%的患者腋窝外发现淋巴结转移。2例腋窝外有前哨淋巴结转移的患者无腋窝转移。
结论
腋窝外前哨淋巴结活检是提高乳腺癌分期准确性的一种潜在手段，因为与单纯腋窝分期相比，它能提供更多信息。
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