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三名曾访问坦桑尼亚的非洲昏睡病患者

[Three patients with African sleeping sickness following a visit to Tanzania].

作者信息

Mendonça Melo M, Rasica M, van Thiel P P A M, Richter C, Kager P A, Wismans P J

机构信息

Havenziekenhuis & Instituut voor Tropische ziekten, afd. Interne Geneeskunde, Haringvliet 2, 3011 TD Rotterdam.

出版信息

Ned Tijdschr Geneeskd. 2002 Dec 28;146(52):2552-6.

Abstract

Three Dutch tourists, a man aged 57 and two women aged 55 en 52 years, acquired African trypanosomiasis in the national parks of Tanzania. Two, without central nervous system involvement, were cured after treatment in the Netherlands, albeit one after having suffered a relapse. In the third patient, involvement of the central nervous system was diagnosed in Africa and she was treated with melarsoprol. After an apparently uneventful recovery she was readmitted with cerebral complaints and symptoms. While being treated with melarsoprol she lapsed into coma. She died following repatriation. An epidemic of trypanosomiasis is currently raging through Central Africa. In several western countries, trypanosomiasis has been diagnosed recently in tourists who visited Tanzania.

摘要

三名荷兰游客,一名57岁男性和两名分别为55岁及52岁的女性,在坦桑尼亚国家公园感染了非洲锥虫病。其中两名没有中枢神经系统受累的游客在荷兰接受治疗后痊愈,尽管其中一人出现了复发。第三名患者在非洲被诊断出中枢神经系统受累,接受了美拉胂醇治疗。在看似顺利康复后,她因脑部不适和症状再次入院。在接受美拉胂醇治疗时陷入昏迷。回国后死亡。目前,锥虫病疫情正在中非肆虐。在几个西方国家,最近在前往坦桑尼亚的游客中诊断出了锥虫病。

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