Chen L C, Gu Y H
Department of Physiology, Beijing Medical University, Beijing 100083.
Sheng Li Ke Xue Jin Zhan. 1999 Apr;30(2):101-6.
Information transmission in the central nervous system relies on neurons working in relays. At chemical synapses information transmission is by means of neurotransmitters, whereas long-distance transmission is carried out by action potentials conducting along nerve fibers. Hence how to pick up and analyze information contained in the spike trains are important topics of several branches of sciences such as neuroscience, bioinformatics, etc. So far there is lack of ideal ways and means. This review briefly introduces the advantages and limitations of the principal coding theories and analyzing methods of information contained in spike trains, and the progress in this field.
中枢神经系统中的信息传递依赖于神经元的接力工作。在化学突触处,信息传递通过神经递质进行,而长距离传递则由沿神经纤维传导的动作电位来完成。因此,如何提取和分析峰电位序列中包含的信息是神经科学、生物信息学等多个学科分支的重要课题。到目前为止,还缺乏理想的方法和手段。本文综述简要介绍了峰电位序列中信息的主要编码理论和分析方法的优缺点以及该领域的进展。