Ravindran B Paul, Singh I Rabi Raja, Brindha S, Sathyan S
Department of Radiation Oncology, CMC Hospital, Vellore 632 004, India.
Phys Med Biol. 2002 Dec 21;47(24):4389-96. doi: 10.1088/0031-9155/47/24/306.
In electron beam therapy, lead or low melting point alloy (LMA) sheet cutouts of sufficient thickness are commonly used to shape the beam. In order to avoid making cutouts for each patient, an attempt has been made to develop a manual multi-leaf collimator for electron beams (eMLC). The eMLC has been developed using LMA for a 15 x 15 cm2 applicator. Electron beam characteristics such as depth dose, beam profiles, surface dose, output factors and virtual source position with the eMLC have been studied and compared with those of an applicator electron beam. The interleaf leakage radiation has also been measured with film dosimetry. Depth dose values obtained using the eMLC were found to be identical to those with the applicator for depths larger than Dmax. However, a decrease in the size of the beam penumbra with the eMLC and increase in the values of surface dose, output factors and virtual source position with eMLC were observed. The leakage between the leaves was less than 5% and the leakage between the opposing leaves was 15%, which could be minimized further by careful positioning of the leaves. It is observed that it is feasible to use such a manual eMLC for patients and eliminate the fabrication of cutouts for each patient.
在电子束治疗中,通常使用具有足够厚度的铅或低熔点合金(LMA)薄片挡块来对射束进行塑形。为了避免为每个患者制作挡块,人们尝试开发一种用于电子束的手动多叶准直器(eMLC)。eMLC是使用LMA为15×15 cm²的施源器开发的。已对eMLC的电子束特性(如深度剂量、射束轮廓、表面剂量、输出因子和虚拟源位置)进行了研究,并与施源器电子束的特性进行了比较。还使用胶片剂量测定法测量了叶片间的泄漏辐射。发现对于大于Dmax的深度,使用eMLC获得的深度剂量值与使用施源器时相同。然而,观察到使用eMLC时射束半值层尺寸减小,且表面剂量、输出因子和虚拟源位置的值增加。叶片间的泄漏小于5%,相对叶片间的泄漏为15%,通过仔细定位叶片可进一步将其最小化。据观察,对患者使用这种手动eMLC并消除为每个患者制作挡块是可行的。