Kelsay Kim
National Jewish Medical and Research Center, 1400 Jackson Street, Suite A206, Denver, CO 80206, USA.
Curr Allergy Asthma Rep. 2003 Jan;3(1):41-6. doi: 10.1007/s11882-003-0011-z.
Food allergies may impact the emotions of patients through both direct and indirect mechanisms. Direct mechanisms include the effects on the central nervous system from biologic mediators released during an allergic reaction to food. Indirect mechanisms include the stress of coping with a food allergy--for example, food preparation and avoidance--as well as managing the fear of the potential consequences of ingesting the food. Indirect effects may also be mediated through family members--for example, the impact of a parent's stress on the child. These relationships are difficult to study, in part because many patients who report food allergy symptoms do not have objective symptoms when challenged with the offending food. Symptoms may be misinterpreted as food allergy more often by patients with certain psychological profiles. In this paper, relevant literature is reviewed, and clinical treatment designed to minimize the emotional suffering of patients and their families is presented through the description of a case vignette.
食物过敏可能通过直接和间接机制影响患者的情绪。直接机制包括食物过敏反应期间释放的生物介质对中枢神经系统的影响。间接机制包括应对食物过敏的压力——例如,食物准备和避免——以及应对摄入该食物可能产生后果的恐惧。间接影响也可能通过家庭成员介导——例如,父母的压力对孩子的影响。这些关系很难研究,部分原因是许多报告有食物过敏症状的患者在接触致病食物时并没有客观症状。具有某些心理特征的患者更常将症状误解为食物过敏。本文回顾了相关文献,并通过一个病例 vignette 的描述,介绍了旨在尽量减少患者及其家人情绪痛苦的临床治疗方法。