Yan X M, Zhang S Q, Chang Q, Liu P, Xu J S
College of Life Science, Nanjing Normal University, Nanjing 210097.
Shi Yan Sheng Wu Xue Bao. 2000 Dec;33(4):309-16.
This paper reports the venom from Agkistrodon halys Pallas have inhibitory activity against fungi and E. coli by tested in a disc diffusion assay. An antibacterial component--LAO from the venom were purified to homogeneous. It had not only antibacterial effect, but L-amino acid oxidase activity. And its enzymatic specific activity was 808 U/mg. The venom had at least 3 antibacterial components (I, II, III) as determined by acid polyacrilamide gel electrophoresis, LAO is the antibaterial components II.
本文报道，通过纸片扩散法检测发现，白眉蝮蛇毒对真菌和大肠杆菌具有抑制活性。从该毒液中纯化得到一种抗菌成分——LAO，使其达到均质状态。它不仅具有抗菌作用，还具有L-氨基酸氧化酶活性，其酶比活性为808 U/mg。通过酸性聚丙烯酰胺凝胶电泳测定，该毒液至少有3种抗菌成分（I、II、III），LAO是抗菌成分II。
Zotero 插件