Kurogouchi Fumio, Tomita Takeshi, Hanaoka Takeshi, Usui Tatsuya, Miyashita Toyohisa, Aruga Masakazu, Katagiri Yuuichi, Takei Manabu, Owa Mafumi, Kiyosawa Kendo
Second Department of Internal Medicine, Shinshu University, School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Nagano-ken, Japan.
Int J Cardiol. 2003 Feb;87(2-3):253-8. doi: 10.1016/s0167-5273(02)00358-3.
Prolongation of total filtered P wave duration (Ad) and low root mean square voltages for the last 20 ms of the P wave (LP20) on a P wave-triggered signal-averaged electrocardiogram (PSAECG) are typically observed in paroxysmal atrial fibrillation (PAF) patients. A shortening of atrial refractoriness and intra-atrial conduction delay (atrial remodeling) have been shown to occur in response to PAF. We, therefore, investigated the effects of spontaneous termination of PAF on the parameters of PSAECG.
We measured the Ad, LP20 and left atrial (LA) diameter by ultrasonic echocardiography before, within 1 h after, and 3 and 12 months after PAF termination in patients with no structural heart disease (n=11).
The PAF duration was 16+/-5 h. The Ads before, within 1 h after, and 3 and 12 months after PAF were 137+/-4, 148+/-4, 137+/-6, and 135+/-7 ms, respectively. The Ad within 1 h after PAF was significantly (P<0.01) longer than at the other three acquisition points. Although the LP20 within 1 h after PAF termination was not significantly different from the other three points, the change in LP20 (within 1 h after PAF-before PAF, -1.1+/-0.4 microV) in the long PAF duration group was significantly (P<0.05) greater than that of the short PAF duration group. LA diameter was unchanged at all points.
These data suggest that PAF results in prolongation of Ad after termination of PAF.
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