Weihe Pál, Debes Froôi, White Roberta F, Sørensen Nicolina, Budtz-Jørgensen Esben, Keiding Niels, Grandjean Philippe
Faerøernes Sygehusvaesen, afdeling for arbejdsmedicin og folkesundhed, Syddansk Universitet, Institut for sundhedstjenesteforskning, og Københavns Universitet, Institut for Folkesundhedsvidenskab, Biostatistisk afdeling.
Ugeskr Laeger. 2003 Jan 6;165(2):107-11.
The central nervous system is particularly vulnerable to prenatal exposure to methylmercury. Due to the widespread exposure to methylmercury from fish, several prospective environmental epidemiology studies have been initiated, in which the maternal exposure during the pregnancy is related to the neurobehavioural development of the children. We have studied a Faroese birth cohort prenatally exposed to methylmercury from maternal intake of contaminated pilot whale meat. At seven years of age, clear dose-response relationships were observed for deficits in attention, language, and memory. An increase in blood pressure was also associated with the prenatal exposure level. The exposure limit for mercury has therefore been decreased.
中枢神经系统特别容易受到产前接触甲基汞的影响。由于鱼类中甲基汞的广泛存在，已经启动了几项前瞻性环境流行病学研究，其中孕期母亲的接触情况与儿童的神经行为发育相关。我们研究了法罗群岛的一个出生队列，这些儿童在产前因母亲摄入受污染的领航鲸肉而接触到甲基汞。在7岁时，观察到注意力、语言和记忆方面的缺陷存在明显的剂量反应关系。血压升高也与产前接触水平有关。因此，汞的接触限值已经降低。
