Anderluh Marija Brecelj, Tchanturia Kate, Rabe-Hesketh Sophia, Treasure Janet
Institute of Psychiatry, King College London, De Crespigny Park.
Am J Psychiatry. 2003 Feb;160(2):242-7. doi: 10.1176/appi.ajp.160.2.242.
The authors retrospectively examined a spectrum of childhood traits that reflect obsessive-compulsive personality in adult women with eating disorders and assessed the predictive value of the traits for the development of eating disorders.
In a case-control design, 44 women with anorexia nervosa, 28 women with bulimia nervosa, and 28 healthy female comparison subjects were assessed with an interview instrument that asked them to recall whether they had experienced various types of childhood behavior suggesting traits associated with obsessive-compulsive personality. The subjects also completed a self-report inventory of obsessive-compulsive disorder (OCD) symptoms.
Childhood obsessive-compulsive personality traits showed a high predictive value for development of eating disorders, with the estimated odds ratio for eating disorders increasing by a factor of 6.9 for every additional trait present. Subjects with eating disorders who reported perfectionism and rigidity in childhood had significantly higher rates of obsessive-compulsive personality disorder and OCD comorbidity later in life, compared with eating disorder subjects who did not report those traits.
Childhood traits reflecting obsessive-compulsive personality appear to be important risk factors for the development of eating disorders and may represent markers of a broader phenotype for a specific subgroup of patients with anorexia nervosa.
作者回顾性研究了一系列反映患有饮食失调症成年女性强迫型人格的童年特质，并评估了这些特质对饮食失调症发展的预测价值。
在一项病例对照设计中，使用一种访谈工具对44名神经性厌食症女性、28名神经性贪食症女性以及28名健康女性对照受试者进行评估，该工具要求她们回忆自己是否经历过各种表明与强迫型人格相关特质的童年行为。受试者还完成了一份强迫症（OCD）症状的自我报告清单。
童年强迫型人格特质对饮食失调症的发展显示出较高的预测价值，每多一种特质，饮食失调症的估计优势比就增加6.9倍。与未报告这些特质的饮食失调症受试者相比，报告童年有完美主义和刻板性的饮食失调症受试者在晚年患强迫型人格障碍和强迫症共病的比例显著更高。
反映强迫型人格的童年特质似乎是饮食失调症发展的重要风险因素，可能代表了神经性厌食症特定亚组患者更广泛表型的标志物。
