Matejcík V
Neurochirurgická klinika LF UKo, FNsP akad. L. Dérera, Bratislava, Slovenská republika.
Rozhl Chir. 2002 Oct;81(10):538-43.
The author presents the results of 32 operations in 30 patients to whom in the course of 11 years, from 1990-2001 by the microtechnique 32 tumours of peripheral nerves of the extremities and the brachial plexus were removed.
In 26 patients 28 tumours of the peripheral nerves of the extremities were removed and in 4 patients 4 tumours of the brachial plexus were removed. Three of the tumours of the brachial plexus spread intraspinally. 31 tumours of the nervous sheaths included 19 schwannomas and 12 neurofibromas. Of 12 neurofibromas six were found in four patients with Recklinghausen's disease (VRD). One patient had a tumour of non-neural elements--a lipoma. The authors did not encounter malignant tumours of nervous sheaths, benign or metastatic malignant ones which compressed or invaded the nerve or plexus. The results were evaluated according to Donner's classification of motor and sensitive functions.
Motor functions improved but remained unaltered in 17 (89%) patients with schwannomas and in 5 (83.3%) patients with pain in the area of the affected nerve either complete or partial mitigation of symptoms occurred. In neurofibromas in 3 (50%) patients motor functions improved or remained unaltered and all patients had a partial or complete regression of painful syndromes. In 4 patients with VRD 6 tumours of the peripheral nerves of the extremities were removed, in all the motor functions improved or remained unalterted and in all a partial or complete regression of pain syndromes was recorded. The results were more favourable in smaller, more distant tumours of the nerve sheaths.
Patients should be operated in departments concerned with problems of peripheral nerves.
作者介绍了1990年至2001年的11年间,对30例患者进行的32例手术的结果,这些患者通过显微技术切除了32例四肢周围神经和臂丛神经肿瘤。
26例患者切除了28例四肢周围神经肿瘤,4例患者切除了4例臂丛神经肿瘤。3例臂丛神经肿瘤向椎管内蔓延。31例神经鞘瘤包括19例施万细胞瘤和12例神经纤维瘤。12例神经纤维瘤中,6例在4例患有冯雷克林霍增氏病(VRD)的患者中发现。1例患者有非神经成分的肿瘤——脂肪瘤。作者未遇到神经鞘的恶性肿瘤,无论是良性还是转移性恶性肿瘤压迫或侵犯神经或神经丛的情况。根据唐纳运动和感觉功能分类对结果进行评估。
施万细胞瘤患者中,17例(89%)运动功能改善但无变化,5例(83.3%)患侧神经区域疼痛的患者症状完全或部分缓解。神经纤维瘤患者中,3例(50%)运动功能改善或无变化,所有患者疼痛综合征部分或完全消退。4例患有VRD的患者切除了6例四肢周围神经肿瘤,所有患者运动功能均改善或无变化,所有患者均记录到疼痛综合征部分或完全消退。神经鞘较小、位置较远的肿瘤结果更理想。
患者应在处理周围神经问题的科室进行手术。