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两种不同脱矿骨基质同种异体移植物治疗局限性干骺端及关节周围缺损的疗效

Efficacy of contained metaphyseal and periarticular defects treated with two different demineralized bone matrix allografts.

作者信息

Cheung S, Westerheide K, Ziran B

机构信息

University of Pittsburgh Medical Center, Department of Orthopaedic Surgery, Suite 1010 Kaufmann Bldg., 3471 Fifth Ave., Pittsburgh, PA 15213, USA.

出版信息

Int Orthop. 2003;27(1):56-9. doi: 10.1007/s00264-002-0388-7. Epub 2002 Sep 17.

Abstract

The efficacies of two different allografts, Grafton (demineralized bone matrix [DBM] in a glycerol carrier) and Orthoblast (DBM in a reverse thermal poloxamer carrier) were examined from cases involving periarticular fractures. Demographic, perioperative, and outcome data for patients with periarticular fractures who underwent a prospectively designed protocol for bone grafting were compiled, with 15 cases using Orthoblast and 13 using Grafton. A successful graft was defined as healing on the first graft attempt without complications. Healing was determined by radiographic studies and clinical evaluation. The successful graft rates of Orthoblast and Grafton were 15/15 and 9/13, respectively.

摘要

从涉及关节周围骨折的病例中,研究了两种不同同种异体移植物(Grafton,甘油载体中的脱矿骨基质[DBM];Orthoblast,反向热泊洛沙姆载体中的DBM)的疗效。收集了接受前瞻性设计骨移植方案的关节周围骨折患者的人口统计学、围手术期和结果数据,其中15例使用Orthoblast,13例使用Grafton。成功的移植定义为首次移植尝试即愈合且无并发症。通过影像学研究和临床评估确定愈合情况。Orthoblast和Grafton的成功移植率分别为15/15和9/13。

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