Tsai Tung-Lung, Lien Chiang-Feng, Guo Yuan-Ching
Department of Otolaryngology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Zhonghua Yi Xue Za Zhi (Taipei). 2002 Nov;65(11):523-8.
Autologous cartilage has been widely used as a material for tympanoplasty and mastoid-obliteration surgery. Since it remains vulnerable to an infectious condition, this study aims to evaluate if it can be used for a chronic suppurative cholesteatomatous ear to achieve single-stage tympanoplasty with mastoidectomy and obliteration of the cavity.
From January 1988 to August 1998, the records of patients with cholesteatoma who received cartilage-obliteration surgery performed by Dr. Lien were examined for any infection-associated problems within three months after the operation. The Fisher's exact test was used to compare the difference in the incidence of post-operative infection-associated problems between suppurative ears and non-suppurative ears.
One hundred and seven surgical procedures performed upon 96 patients were included in this study, with 97 being primary surgical procedures and ten being revision surgery for previous open cavity with cholesteatoma recurrences. The average follow-up was 47.7 months. At time of surgery, there were 59 non-suppurative ears; 48 ears were suppurative and cultured. Granulations were found in the middle ear or mastoid for 42 ears (39.3%). Five ears (4.7%) exhibited infection-associated post-operative problems within three post-operative months. Three cases (5.1%) were non-suppurative ears and two cases (4.2%) were suppurative ears. There was no significant statistical difference when examined with the Fisher's Exact test.
In an immunocompetent patient with a cholesteatomatous chronic suppurative ear, autologous cartilage could potentially tolerate an infection condition to serve as a material for mastoid-obliteration in a single-stage surgical procedure.
自体软骨已被广泛用作鼓室成形术和乳突充填手术的材料。由于其仍易受感染,本研究旨在评估其是否可用于慢性化脓性胆脂瘤型中耳,以实现乳突根治鼓室成形及乳突腔充填一期手术。
回顾1988年1月至1998年8月间由连医生施行软骨充填手术的胆脂瘤患者记录,观察术后3个月内任何与感染相关的问题。采用Fisher精确检验比较化脓性耳和非化脓性耳术后感染相关问题发生率的差异。
本研究纳入96例患者的107例手术,其中97例为初次手术,10例为因胆脂瘤复发对既往开放乳突腔行翻修手术。平均随访47.7个月。手术时,59耳为非化脓性,48耳为化脓性并进行了培养。42耳(39.3%)中耳或乳突发现肉芽组织。5耳(4.7%)术后3个月内出现与感染相关的术后问题,其中3例(5.1%)为非化脓性耳,2例(4.2%)为化脓性耳。Fisher精确检验显示无显著统计学差异。
在免疫功能正常的慢性化脓性胆脂瘤型中耳患者中,自体软骨有可能耐受感染,可作为一期手术乳突充填材料。