Zupanets I A, Bezdetko N V, Dedukh N V, Otrishko I A
Clinical Pharmacy Department, National Pharmaceutical Academy of Ukraine, ul. Pushkinskaya 53, Kharkov 61002, Ukraine.
Eksp Klin Farmakol. 2002 Nov-Dec;65(6):67-9.
The effects of glucosamine hydrochloride on the metabolic and repair processes were studied on a model of post-traumatic osteoarthrosis in the articular cartilage and on a model of post-traumatic keratitis in the cornea. The administration of glucosamine hydrochloride stimulated repair and favored inhibition of dystrophic post-traumatic processes in the connective-tissue structures. It is suggested that a probable mechanism of the drug action consists in stimulation of the synthesis of glucosaminoglycanes and collagen.