Crawford Andrew S, White Joseph G
Department of Gastroenterology, Texas A&M University/Scott & White Memorial Hospital, Temple, USA.
South Med J. 2002 Dec;95(12):1444-6.
COX-2 inhibitors are a new class of nonsteroidal anti-inflammatory drugs with a reported benefit of less gastric and duodenal ulceration and hemorrhage. We describe a 67-year-old man taking a higher than usual dose of celecoxib (Celebrex) for osteoarthritis with resultant gastric erosions, ulceration, and a significant gastrointestinal (GI) hemorrhage.