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Celecoxib-induced upper gastrointestinal hemorrhage and ulceration.

作者信息

Crawford Andrew S, White Joseph G

机构信息

Department of Gastroenterology, Texas A&M University/Scott & White Memorial Hospital, Temple, USA.

出版信息

South Med J. 2002 Dec;95(12):1444-6.

Abstract

COX-2 inhibitors are a new class of nonsteroidal anti-inflammatory drugs with a reported benefit of less gastric and duodenal ulceration and hemorrhage. We describe a 67-year-old man taking a higher than usual dose of celecoxib (Celebrex) for osteoarthritis with resultant gastric erosions, ulceration, and a significant gastrointestinal (GI) hemorrhage.

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