成瘾性药物和压力会引发腹侧被盖区突触的共同变化。
Addictive drugs and stress trigger a common change at VTA synapses.
作者信息
Kauer Julie A
机构信息
Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI 02912, USA.
出版信息
Neuron. 2003 Feb 20;37(4):549-50. doi: 10.1016/s0896-6273(03)00087-4.
Abstract
In this issue of Neuron, Saal et al. find that exposure to any of five addictive drugs or exposure to a brief stressor produces a shared cellular modification of excitatory synapses in the ventral tegmental area (VTA). This common response may represent a starting point for dissecting early changes that underlie addiction.
摘要
在本期《神经元》杂志中，萨尔等人发现，暴露于五种成瘾性药物中的任何一种或暴露于短暂应激源都会在腹侧被盖区（VTA）产生兴奋性突触的共同细胞修饰。这种共同反应可能是剖析成瘾潜在早期变化的起点。
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